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Assay Detail

CHEMBL5528097

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antileishmanial activity against Leishmania donovani 9515 amastigotes assessed as inhibition of parasite growth incubated for 48 hrs by resazurin dye based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania donovani
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania donovani (CHEMBL367)
Type ORGANISM
Organism Leishmania donovani

Publication

Synthetic product-based approach toward potential antileishmanial drug development.
Pal R, Teli G, Akhtar MJ, Matada GSP.
Eur J Med Chem (2024) 263 : 115927 -115927
PubMed 37976706 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.13 7.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5565124 1 7.05
CHEMBL5563463 1 5.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5565124 IC50 = 90.0 nM 7.05
CHEMBL5563463 IC50 = 6290.0 nM 5.20