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Assay Detail

CHEMBL5528683

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of electric eel AChE
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Electrophorus electricus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL4078)
Type SINGLE PROTEIN
Organism Electrophorus electricus

Publication

Discovery of novel deoxyvasicinone derivatives with benzenesulfonamide substituents as multifunctional agents against Alzheimer's disease.
Dong S, Xia J, Wang F, Yang L, Xing S, Du J, Zhang T, Li Z.
Eur J Med Chem (2024) 264 : 116013 -116013
PubMed 38052155 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.08 4.08

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL456881 DEOXYVASICINONE 1 4.08

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL456881 DEOXYVASICINONE IC50 = 82500.0 nM 4.08