Assay Detail
Binding
CHEMBL5531434
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist potency at GPR183 (unknown origin) transfected in HEK293 cells by schild plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Highly Potent Oxysterol Receptor GPR183 Antagonist Bearing the Benzo[<i>d</i>]thiazole Structural Motif for the Treatment of Inflammatory Bowel Disease (IBD).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 9.21 | 9.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5567610 | — | — | 1 | 9.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5567610 | — | Kd | = | 0.6166 | nM | 9.21 |