Assay Detail

CHEMBL5532875

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Functional

Antileishmanial activity against Leishmania donovani amastigotes

ChEMBL ↗

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Target

Leishmania donovani (CHEMBL367) ↗

Open DB target context

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Leishmania donovani (CHEMBL367) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Leishmania donovani

CHEMBL367

Anchored from Assay target.

Protein identity Leishmania donovani

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Leishmania donovani
Confidence	1 — Organism
Curated By	Autocuration

Target

Leishmania donovani (CHEMBL367) ↗

Type	ORGANISM
Organism	Leishmania donovani

Publication

The role of natural anti-parasitic guided development of synthetic drugs for leishmaniasis.

Pal R, Teli G, Akhtar MJ, Matada GSP.
Eur J Med Chem (2023) 258 : 115609 -115609
PubMed 37421889 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	6.48	6.48

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL490355	SULFURETIN	—	1	6.48

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL490355	SULFURETIN	EC50	=	330.0	nM	6.48