Assay Detail
Functional
CHEMBL5532880
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Antileishmanial activity Leishmania infantum promastigotes assessed as reduction in parasite growth incubated for 72 hrs by alamar blue assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The role of natural anti-parasitic guided development of synthetic drugs for leishmaniasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.85 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL325864 | SCOPARONE | — | 1 | 5.28 |
| CHEMBL5275722 | — | — | 1 | 4.70 |
| CHEMBL5568929 | — | — | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL325864 | SCOPARONE | EC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL5275722 | — | EC50 | = | 20200.0 | nM | 4.70 |
| CHEMBL5568929 | — | EC50 | = | 26200.0 | nM | 4.58 |