Assay Detail
Binding
CHEMBL5533406
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Inhibition of GSK3beta (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 9.29 | 9.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5413819 | — | — | 1 | 9.82 |
| CHEMBL5404581 | — | — | 1 | 9.82 |
| CHEMBL5419652 | — | — | 1 | 9.46 |
| CHEMBL5270781 | — | — | 1 | 9.14 |
| CHEMBL5278465 | — | — | 1 | 8.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5413819 | — | IC50 | = | 0.15 | nM | 9.82 |
| CHEMBL5404581 | — | IC50 | = | 0.15 | nM | 9.82 |
| CHEMBL5419652 | — | IC50 | = | 0.35 | nM | 9.46 |
| CHEMBL5270781 | — | IC50 | = | 0.73 | nM | 9.14 |
| CHEMBL5278465 | — | IC50 | = | 5.9 | nM | 8.23 |