Assay Detail
Binding
CHEMBL5533423
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Inhibition of human P38 MAPK by ADP-Glo kinase assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.32 | 6.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5569575 | — | — | 1 | 6.97 |
| CHEMBL1258904 | — | — | 1 | 6.57 |
| CHEMBL1233747 | — | — | 1 | 5.43 |
| CHEMBL4215895 | — | — | 1 | - |
| CHEMBL4753641 | — | — | 1 | - |
| CHEMBL4778645 | — | — | 1 | - |
| CHEMBL4784092 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5569575 | — | IC50 | = | 106.0 | nM | 6.97 |
| CHEMBL1258904 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL1233747 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL4215895 | — | IC50 | < | 10000.0 | nM | - |
| CHEMBL4753641 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL4778645 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL4784092 | — | IC50 | > | 20000.0 | nM | - |