Assay Detail
Binding
CHEMBL5533432
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of JNK2 (unknown origin) by discoverX kinomescan assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.88 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5569575 | — | — | 1 | 8.30 |
| CHEMBL4778645 | — | — | 1 | 7.48 |
| CHEMBL4753641 | — | — | 1 | 7.46 |
| CHEMBL4784092 | — | — | 1 | 7.28 |
| CHEMBL3355181 | — | — | 1 | 6.69 |
| CHEMBL5572325 | — | — | 1 | 4.07 |
| CHEMBL3355178 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5569575 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL4778645 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL4753641 | — | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL4784092 | — | IC50 | = | 53.0 | nM | 7.28 |
| CHEMBL3355181 | — | IC50 | = | 206.0 | nM | 6.69 |
| CHEMBL5572325 | — | IC50 | = | 85210.0 | nM | 4.07 |
| CHEMBL3355178 | — | IC50 | < | 0.1 | nM | - |