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Assay Detail

CHEMBL5533910

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DNMT3B/3L (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

DNMT3B-DNMT3L complex (CHEMBL3885560)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Dual inhibitors of HDAC and other epigenetic regulators: A novel strategy for cancer treatment.
Shirbhate E, Singh V, Jahoriya V, Mishra A, Veerasamy R, Tiwari AK, Rajak H.
Eur J Med Chem (2024) 263 : 115938 -115938
PubMed 37989059 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.88 5.88

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5575739 1 5.88

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5575739 IC50 = 1320.0 nM 5.88