Assay Detail
Functional
CHEMBL5534282
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human GIPR receptor expressed in HEK293 cells assessed as cAMP level measured after 60 mins by HTRF based assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gastric inhibitory polypeptide receptor (CHEMBL4383) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of a Novel Glucagon-like Peptide-1 (GLP-1) Analogue from Bullfrog and Investigation of Its Potential for Designing GLP-1-Based Multiagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 9.29 | 10.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5590721 | — | — | 1 | 10.66 |
| CHEMBL5575146 | — | — | 1 | 9.22 |
| CHEMBL5563008 | — | — | 1 | 9.08 |
| CHEMBL5593907 | — | — | 1 | 9.05 |
| CHEMBL5579680 | — | — | 1 | 9.02 |
| CHEMBL5575699 | — | — | 1 | 9.01 |
| CHEMBL5571645 | — | — | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5590721 | — | EC50 | = | 0.022 | nM | 10.66 |
| CHEMBL5575146 | — | EC50 | = | 0.6 | nM | 9.22 |
| CHEMBL5563008 | — | EC50 | = | 0.83 | nM | 9.08 |
| CHEMBL5593907 | — | EC50 | = | 0.89 | nM | 9.05 |
| CHEMBL5579680 | — | EC50 | = | 0.96 | nM | 9.02 |
| CHEMBL5575699 | — | EC50 | = | 0.97 | nM | 9.01 |
| CHEMBL5571645 | — | EC50 | = | 0.99 | nM | 9.00 |