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Assay Detail

CHEMBL5534745

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against wild type Acinetobacter baumannii ATCC 17978 assessed as inhibition of microbial growth measured after 24 hrs by broth microdilution method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Acinetobacter baumannii
Confidence 1 — Organism
Curated By Autocuration

Target

Acinetobacter baumannii (CHEMBL614425)
Type ORGANISM
Organism Acinetobacter baumannii

Publication

Guiding the Way: Traditional Medicinal Chemistry Inspiration for Rational Gram-Negative Drug Design.
Stoorza AM, Duerfeldt AS.
J Med Chem (2024) 67 : 65 -80
PubMed 38134355 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.72 4.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5197931 1 4.72
CHEMBL5180857 1 4.72
CHEMBL5178366 1 4.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5197931 IC50 = 19000.0 nM 4.72
CHEMBL5180857 IC50 = 19000.0 nM 4.72
CHEMBL5178366 IC50 = 19000.0 nM 4.72