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Assay Detail

CHEMBL5535210

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PI3K (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Comprehensive Insights that Targeting PIM for Cancer Therapy: Prospects and Obstacles.
Chen L, Mao W, Ren C, Li J, Zhang J.
J Med Chem (2024) 67 : 38 -64
PubMed 38164076 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.84 9.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4878958 1 9.89
CHEMBL4869696 1 7.78

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4878958 IC50 = 0.13 nM 9.89
CHEMBL4869696 IC50 = 16.8 nM 7.78