Assay Detail
Binding
CHEMBL5536066
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of G9a (685 to 1000 residues ) (unknown origin) expressed in Escherichia coli BL21 using H3(1 to 20)cys as substrate by spectrometry based analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase EHMT2 (CHEMBL6032) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
SETDB1 as a cancer target: challenges and perspectives in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.53 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL569864 | — | — | 1 | 5.72 |
| CHEMBL1797937 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL569864 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL1797937 | — | IC50 | = | 4700.0 | nM | 5.33 |