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Assay Detail

CHEMBL5536070

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to G9a (unknown origin) assessed as inhibition constant measured after 20 mins by fluorescence based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histone-lysine N-methyltransferase EHMT2 (CHEMBL6032)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

SETDB1 as a cancer target: challenges and perspectives in drug design.
Hassanie H, Penteado AB, de Almeida LC, Calil RL, da Silva Emery F, Costa-Lotufo LV, Trossini GHG.
RSC Med Chem (2024) 15 : 1424 -1451
PubMed 38799223 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1231795 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1231795 Ki = 3.0 nM 8.52