Assay Detail
Binding
CHEMBL5536072
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GLP (unknown origin) using H3(1 to 25) as peptide substrate and SAM as cosubstrate measured after 20 mins by fluorescence based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase EHMT1 (CHEMBL6031) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
SETDB1 as a cancer target: challenges and perspectives in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.72 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1231795 | — | — | 1 | 7.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1231795 | — | IC50 | = | 19.0 | nM | 7.72 |