Assay Detail
Binding
CHEMBL5536075
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Binding affinity to SETDB1 (unknown origin) assessed as dissociation constant by surface plasmon resonance analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase SETDB1 (CHEMBL2321646) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
SETDB1 as a cancer target: challenges and perspectives in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.06 | 6.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5572139 | — | — | 1 | 6.63 |
| CHEMBL5564879 | — | — | 1 | 5.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5572139 | — | Kd | = | 232.0 | nM | 6.63 |
| CHEMBL5564879 | — | Kd | = | 3260.0 | nM | 5.49 |