Assay Detail
Binding
CHEMBL5536076
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SETDB1 (unknown origin) using histone H3 as substrate measured after 1.5 hrs by SpectraMax microplate reader analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase SETDB1 (CHEMBL2321646) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
SETDB1 as a cancer target: challenges and perspectives in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.19 | 4.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5572230 | — | — | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5572230 | — | IC50 | = | 65000.0 | nM | 4.19 |