Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5536082

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of SUV39H1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histone-lysine N-methyltransferase SUV39H1 (CHEMBL1795118)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

SETDB1 as a cancer target: challenges and perspectives in drug design.
Hassanie H, Penteado AB, de Almeida LC, Calil RL, da Silva Emery F, Costa-Lotufo LV, Trossini GHG.
RSC Med Chem (2024) 15 : 1424 -1451
PubMed 38799223 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.10 6.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1089316 CHAETOCIN 1 6.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1089316 CHAETOCIN IC50 = 800.0 nM 6.10