Assay Detail
Binding
CHEMBL5536377
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to recombinant His-tagged human TIM-3 expressed in HEK293 assessed as dissociation constant by microscale thermophoresis analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Hepatitis A virus cellular receptor 2 (CHEMBL4630879) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-Based Rational Design of Constrained Peptides as TIM-3 Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.66 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5571782 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5571782 | — | Kd | = | 217.0 | nM | 6.66 |