Assay Detail
Functional
CHEMBL5536641
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Antiproliferative activity against human SPEC-2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SPEC-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecule targeted therapies for endometrial cancer: progress, challenges, and opportunities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.18 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4650311 | ONC-206 | 1.0 | 1 | 6.62 |
| CHEMBL4297310 | DORDAVIPRONE | 3.0 | 1 | 5.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4650311 | ONC-206 | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL4297310 | DORDAVIPRONE | IC50 | = | 1810.0 | nM | 5.74 |