Assay Detail
Functional
CHEMBL5536992
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Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potential of covalently linked tamoxifen hybrids for cancer treatment: recent update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.98 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5572046 | — | — | 1 | 8.30 |
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 8.10 |
| CHEMBL1093458 | ENDOXIFEN | 3.0 | 1 | 7.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5572046 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL1093458 | ENDOXIFEN | IC50 | = | 29.0 | nM | 7.54 |