Assay Detail
Functional
CHEMBL5537270
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against SARS-CoV-2 UC-1074 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by microscopic analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Natural products as potential lead compounds to develop new antiviral drugs over the past decade.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.99 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL164 | MYRICETIN | — | 1 | 5.10 |
| CHEMBL3348861 | AMPELOPSIN | 2.0 | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL164 | MYRICETIN | EC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL3348861 | AMPELOPSIN | EC50 | = | 13560.0 | nM | 4.87 |