Assay Detail
Functional
CHEMBL5537274
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against SARS-CoV-2 infected in African green monkey Vero cells assessed as reduction in viral replication
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Natural products as potential lead compounds to develop new antiviral drugs over the past decade.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.46 | 7.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL255708 | CEPHAELINE | — | 1 | 7.91 |
| CHEMBL400092 | LYCORINE | — | 1 | 6.36 |
| CHEMBL50588 | EMETINE | 4.0 | 1 | 5.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL255708 | CEPHAELINE | EC50 | = | 12.3 | nM | 7.91 |
| CHEMBL400092 | LYCORINE | EC50 | = | 439.0 | nM | 6.36 |
| CHEMBL50588 | EMETINE | EC50 | = | 7710.0 | nM | 5.11 |