Assay Detail

CHEMBL5537357

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Functional

Antiviral activity against SARS-CoV-2 infected in human HPAEpiC cells assessed as reduction in viral growth

ChEMBL ↗

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Target

SARS-CoV-2 (CHEMBL4303835) ↗

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Primary target SARS-CoV-2

CHEMBL4303835

Anchored from Assay target.

Protein identity SARS-CoV-2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Severe acute respiratory syndrome coronavirus 2
Confidence	1 — Organism
Curated By	Autocuration

Target

SARS-CoV-2 (CHEMBL4303835) ↗

Type	ORGANISM
Organism	Severe acute respiratory syndrome coronavirus 2

Publication

Structure and function of SARS-CoV and SARS-CoV-2 main proteases and their inhibition: A comprehensive review.

Li X, Song Y.
Eur J Med Chem (2023) 260 : 115772 -115772
PubMed 37659195 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.92	8.92

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5195325	—	—	1	8.92

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5195325	—	EC50	=	1.2	nM	8.92