Assay Detail

CHEMBL5537510

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Binding

Inhibition of Hepatitis C virus NS3 protease

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Hepacivirus hominis
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.

Niu ZX, Nie P, Herdewijn P, Wang YT.
Eur J Med Chem (2023) 262 : 115919 -115919
PubMed 37922830 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.70	9.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2105735	ASUNAPREVIR	4.0	1	9.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2105735	ASUNAPREVIR	IC50	=	0.2	nM	9.70