Assay Detail
Binding
CHEMBL5537516
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Inhibition of Hepatitis C virus genotype 3a NS4B
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.00 | 9.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2146090 | DANOPREVIR SODIUM | -1.0 | 2 | 9.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2146090 | DANOPREVIR SODIUM | IC50 | = | 0.29 | nM | 9.54 |
| CHEMBL2146090 | DANOPREVIR SODIUM | IC50 | = | 3.5 | nM | 8.46 |