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Assay Detail

CHEMBL5537525

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Hepatitis C virus NS2B-NS3 protease assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepacivirus hominis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.
Niu ZX, Nie P, Herdewijn P, Wang YT.
Eur J Med Chem (2023) 262 : 115919 -115919
PubMed 37922830 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.22 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1255891 NARLAPREVIR 3.0 1 8.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1255891 NARLAPREVIR Ki = 6.0 nM 8.22