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Assay Detail

CHEMBL5537528

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-2 infected in african green monkey Vero E6 cells assessed as reduction in viral replication
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.
Niu ZX, Nie P, Herdewijn P, Wang YT.
Eur J Med Chem (2023) 262 : 115919 -115919
PubMed 37922830 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.11 8.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3137358 SIMEPREVIR SODIUM 4.0 1 8.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3137358 SIMEPREVIR SODIUM EC50 = 7.8 nM 8.11