Assay Detail
Binding
CHEMBL5537529
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Hepatitis C virus genotype 1H NS3-4A protease assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
Hepatitis C virus serine protease, NS3/NS4A (CHEMBL2095231) ↗| Type | PROTEIN COMPLEX |
| Organism | Hepatitis C virus |
Publication
Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.15 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL231813 | TELAPREVIR | 4.0 | 1 | 8.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL231813 | TELAPREVIR | Ki | = | 7.0 | nM | 8.15 |