Assay Detail
Functional
CHEMBL5539895
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against SARS-CoV-2 infected in human Huh-7 cells assessed as reduction in viral growth
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Hepatitis C: The Story of a Long Journey through First, Second, and Third Generation NS3/4A Peptidomimetic Inhibitors. What Did We Learn?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.76 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL414993 | — | — | 1 | 8.40 |
| CHEMBL3125106 | — | — | 1 | 7.72 |
| CHEMBL1956820 | GS-9256 | 2.0 | 1 | 7.70 |
| CHEMBL3128331 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL414993 | — | EC50 | = | 4.0 | nM | 8.40 |
| CHEMBL3125106 | — | EC50 | = | 19.0 | nM | 7.72 |
| CHEMBL1956820 | GS-9256 | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL3128331 | — | EC50 | = | 60.0 | nM | 7.22 |