Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5539899

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-2 infected in African green monkey Vero cells assessed as reduction in viral replication measured after 72 hrs by qRT-PCR analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Hepatitis C: The Story of a Long Journey through First, Second, and Third Generation NS3/4A Peptidomimetic Inhibitors. What Did We Learn?
Martino SD, Petri GL, De Rosa M.
J Med Chem (2024) 67 : 885 -921
PubMed 38179950 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.80 8.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4297647 FURAPREVIR 3.0 1 8.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4297647 FURAPREVIR EC50 = 1.6 nM 8.80