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Assay Detail

CHEMBL5541274

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human BXPC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type BXPC-3
Confidence 1 — Organism
Curated By Autocuration

Target

BXPC-3 (CHEMBL614530)
Type CELL-LINE
Organism Homo sapiens

Publication

Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in Pancreatic Cancer Therapy.
Tang Z, Li J, Peng L, Xu F, Tan Y, He X, Zhu C, Zhang ZM, Zhang Z, Sun P, Ding K, Li Z.
J Med Chem (2024) 67 : 1872 -1887
PubMed 38265413 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.70 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5569478 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5569478 IC50 = 20.0 nM 7.70