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Assay Detail

CHEMBL5543237

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human Neutrophil elastase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type Neutrophil
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Neutrophil elastase (CHEMBL248)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of anti-inflammatory natural flavonoids: Diverse scaffolds and promising leads for drug discovery.
Li J, Zhao R, Miao P, Xu F, Chen J, Jiang X, Hui Z, Wang L, Bai R.
Eur J Med Chem (2023) 260 : 115791 -115791
PubMed 37683361 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.46 6.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL75978 5-DEMETHYLNOBILETIN 1 6.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL75978 5-DEMETHYLNOBILETIN IC50 = 350.0 nM 6.46