Assay Detail
Binding
CHEMBL5543337
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant HDAC2 using Ac-RHKK(Acetyl)-AMC peptide as fluorogenic substrate pre-incubated for 30 mins followed by substrate addition and measured for 60 mins by fluorescence based analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Technologies of targeting histone deacetylase in drug discovery: Current progress and emerging prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.48 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4788954 | — | — | 1 | 8.40 |
| CHEMBL5570728 | — | — | 1 | 6.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4788954 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL5570728 | — | IC50 | = | 280.0 | nM | 6.55 |