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Assay Detail

CHEMBL5543446

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type K562
Confidence 1 — Organism
Curated By Autocuration

Target

K562 (CHEMBL385)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advances of antitumor leading compound Erianin: Mechanisms of action and structural modification.
Ma L, Li M, Zhang Y, Liu K.
Eur J Med Chem (2023) 261 : 115844 -115844
PubMed 37804769 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 9.59 9.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5575069 1 9.62
CHEMBL4458738 1 9.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5575069 IC50 = 0.24 nM 9.62
CHEMBL4458738 IC50 = 0.28 nM 9.55