Assay Detail
Binding
CHEMBL5543460
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of His-tagged human recombinant Hsp70 (1 to 381 residues) expressed in HeLa cells incubated for 1 hr by fluorescence polarization assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Small molecules targeting molecular chaperones for tau regulation: Achievements and challenges.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.94 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL261368 | AZURE C | — | 1 | 4.96 |
| CHEMBL164 | MYRICETIN | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL261368 | AZURE C | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL164 | MYRICETIN | EC50 | = | 12000.0 | nM | 4.92 |