Assay Detail
Binding
CHEMBL5543490
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Inhibition of COX-2 (unknown origin) by Enzyme immune assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Dual COX-2/15-LOX inhibitors: A new avenue in the prevention of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.71 | 8.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5592921 | — | — | 1 | 8.75 |
| CHEMBL1562610 | MECLOFENAMATE SODIUM | 4.0 | 1 | 8.25 |
| CHEMBL5174073 | — | — | 1 | 8.19 |
| CHEMBL5572235 | — | — | 1 | 8.19 |
| CHEMBL5193790 | — | — | 1 | 8.19 |
| CHEMBL5594504 | — | — | 1 | 8.19 |
| CHEMBL5275045 | — | — | 1 | 5.96 |
| CHEMBL5280862 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5592921 | — | IC50 | = | 1.77 | nM | 8.75 |
| CHEMBL1562610 | MECLOFENAMATE SODIUM | IC50 | = | 5.64 | nM | 8.25 |
| CHEMBL5174073 | — | IC50 | = | 6.4 | nM | 8.19 |
| CHEMBL5572235 | — | IC50 | = | 6.4 | nM | 8.19 |
| CHEMBL5193790 | — | IC50 | = | 6.4 | nM | 8.19 |
| CHEMBL5594504 | — | IC50 | = | 6.4 | nM | 8.19 |
| CHEMBL5275045 | — | IC50 | = | 1110.0 | nM | 5.96 |
| CHEMBL5280862 | — | IC50 | = | 1110.0 | nM | 5.96 |