Assay Detail
Functional
CHEMBL5543516
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Cytotoxicity against human Mononuclear cell line assessed as reduction in cell viability incubated for 18 to 20 hrs by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Mononuclear cell line |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dual COX-2/15-LOX inhibitors: A new avenue in the prevention of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 6.60 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5567134 | — | — | 1 | 6.60 |
| CHEMBL5562807 | — | — | 1 | 6.60 |
| CHEMBL5571135 | — | — | 1 | 6.60 |
| CHEMBL5575997 | — | — | 1 | 6.60 |
| CHEMBL5567478 | — | — | 1 | 6.60 |
| CHEMBL5569922 | — | — | 1 | 6.60 |
| CHEMBL5575352 | — | — | 1 | 6.60 |
| CHEMBL5574681 | — | — | 1 | 6.60 |
| CHEMBL5590246 | — | — | 1 | 6.60 |
| CHEMBL5570162 | — | — | 1 | 6.60 |
| CHEMBL5574242 | — | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5567134 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5562807 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5571135 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5575997 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5567478 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5569922 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5575352 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5574681 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5590246 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5570162 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5574242 | — | IC50 | = | 250.0 | nM | 6.60 |