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Assay Detail

CHEMBL5546302

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Functional
Cytotoxicity against human HPAC cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HPAC
Confidence 1 — Organism
Curated By Autocuration

Target

HPAC (CHEMBL612595)
Type CELL-LINE
Organism Homo sapiens

Publication

Lead Compound Development of SRC-3 Inhibitors with Improved Pharmacokinetic Properties and Anticancer Efficacy.
Lu D, Chen J, Qin L, Bijou I, Yi P, Li F, Song X, MacKenzie KR, Yu X, Yang B, Roy Chowdhury S, Korp JD, O'Malley BW, Lonard DM, Wang J.
J Med Chem (2024) 67 : 5333 -5350
PubMed 38551814 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.58 7.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5590309 1 7.58
CHEMBL5570209 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5590309 IC50 = 26.0 nM 7.58
CHEMBL5570209 IC50 - -