Assay Detail
Binding
CHEMBL5546600
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK7/CycH/MAT1 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Recent Discovery and Development of Inhibitors that Target CDK9 and Their Therapeutic Indications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.57 | 7.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4763663 | — | — | 1 | 7.03 |
| CHEMBL5573310 | — | — | 1 | 6.40 |
| CHEMBL1922219 | — | — | 1 | 6.28 |
| CHEMBL4442620 | RONICICLIB | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4763663 | — | IC50 | = | 93.0 | nM | 7.03 |
| CHEMBL5573310 | — | IC50 | = | 398.0 | nM | 6.40 |
| CHEMBL1922219 | — | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL4442620 | RONICICLIB | IC50 | < | 25.0 | nM | - |