Assay Detail
Functional
CHEMBL5546601
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human A498 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A498 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent Discovery and Development of Inhibitors that Target CDK9 and Their Therapeutic Indications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.24 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4525049 | — | — | 1 | 7.24 |
| CHEMBL5570279 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4525049 | — | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL5570279 | — | IC50 | < | 700.0 | nM | - |