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Assay Detail

CHEMBL5546604

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK2/CYCA (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Recent Discovery and Development of Inhibitors that Target CDK9 and Their Therapeutic Indications.
Zhang Y, Shan L, Tang W, Ge Y, Li C, Zhang J.
J Med Chem (2024) 67 : 5185 -5215
PubMed 38564299 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.29 7.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5563573 1 7.33
CHEMBL5287796 1 5.93
CHEMBL3263773 1 5.61

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5563573 IC50 = 47.0 nM 7.33
CHEMBL5287796 IC50 = 1180.0 nM 5.93
CHEMBL3263773 IC50 = 2441.0 nM 5.61