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Assay Detail

CHEMBL5547002

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human CAKI-1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CAKI-1
Confidence 1 — Organism
Curated By Autocuration

Target

CAKI-1 (CHEMBL614067)
Type CELL-LINE
Organism Homo sapiens

Publication

Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death.
Velma GR, Krider IS, Alves ETM, Courey JM, Laham MS, Thatcher GRJ.
J Med Chem (2024) 67 : 5999 -6026
PubMed 38580317 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.22 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4546918 1 6.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4546918 IC50 = 600.0 nM 6.22