Assay Detail
Binding
CHEMBL5548019
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human FGFR2 in presence of ATP by hotspot assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on S<sub>N</sub>Ar Electrophiles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.31 | 6.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5571683 | — | — | 1 | 6.31 |
| CHEMBL5570033 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5571683 | — | IC50 | = | 490.0 | nM | 6.31 |
| CHEMBL5570033 | — | IC50 | > | 5000.0 | nM | - |