Assay Detail
Binding
CHEMBL5548762
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Inhibition of Helicobacter pylori XGHPRT by spectrophotometry
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Helicobacter pylori |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.29 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5565343 | — | — | 1 | 7.00 |
| CHEMBL5573402 | — | — | 1 | 7.00 |
| CHEMBL5563998 | — | — | 1 | 6.00 |
| CHEMBL5591537 | — | — | 1 | 5.16 |
| CHEMBL5569467 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5565343 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL5573402 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL5563998 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL5591537 | — | Ki | = | 7000.0 | nM | 5.16 |
| CHEMBL5569467 | — | Ki | > | 10000.0 | nM | - |