Assay Detail
Functional
CHEMBL5549033
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Antiproliferative activity against human MOLT-4 cells assessed as reduction in cell viability incubated for 72 hrs by CellTiter-Glo Luminescent assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLT-4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent Progress in DNA Damage Response-Targeting PROTAC Degraders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.26 | 6.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4638510 | — | — | 1 | 6.41 |
| CHEMBL1976040 | ADAVOSERTIB | 2.0 | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4638510 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL1976040 | ADAVOSERTIB | IC50 | = | 800.0 | nM | 6.10 |