Assay Detail
Functional
CHEMBL5550446
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Antiproliferative activity against human U2OS cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U2OS |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of 1H-pyrrolo[3,2-g]isoquinolines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.45 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5178368 | — | — | 1 | 6.05 |
| CHEMBL5594716 | — | — | 1 | 5.57 |
| CHEMBL5181620 | — | — | 1 | 5.23 |
| CHEMBL5570490 | — | — | 1 | 4.95 |
| CHEMBL5592689 | — | — | 1 | - |
| CHEMBL5563473 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5178368 | — | EC50 | = | 900.0 | nM | 6.05 |
| CHEMBL5594716 | — | EC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL5181620 | — | EC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL5570490 | — | EC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL5592689 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL5563473 | — | EC50 | > | 50000.0 | nM | - |