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Assay Detail

CHEMBL5552663

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Poly (ADP-ribose) polymerase (PARP) inhibitors as anticancer agents: An outlook on clinical progress, synthetic strategies, biological activity, and structure-activity relationship.
Das PK, Matada GSP, Pal R, Maji L, Dhiwar PS, Manjushree BV, Viji MP.
Eur J Med Chem (2024) 274 : 116535 -116535
PubMed 38838546 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.37 5.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5274451 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5274451 IC50 = 4250.0 nM 5.37