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Assay Detail

CHEMBL5552953

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Functional
Antiproliferative activity against human A549 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Rutaecarpine-inspired scaffold-hopping strategy and Ullmann cross-coupling based synthetic approach: Identification of pyridopyrimidinone-indole based novel anticancer chemotypes.
Yadav M, Roy N, Mandal K, Nagpure M, Santra MK, Guchhait SK.
Bioorg Med Chem (2024) 109 : 117799 -117799
PubMed 38897138 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.89 5.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL81925 1 5.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL81925 IC50 = 1300.0 nM 5.89