Assay Detail
Functional
CHEMBL5553516
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against RSV A2 infected in D-HBE-As cells assessed as inhibition of intracellular virus replication
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Respiratory syncytial virus |
| Cell Type | D-HBE-As |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Respiratory syncytial virus (CHEMBL612679) ↗| Type | ORGANISM |
| Organism | Respiratory syncytial virus |
Publication
Discovery of GS-7682, a Novel 4'-Cyano-Modified <i>C</i>-Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.01 | 7.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5562532 | — | — | 1 | 7.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5562532 | — | IC50 | = | 97.0 | nM | 7.01 |